Công thức chung:

In spte of/ Despite + N, S-V : Mặc dù.............mà

Although/ Eventhough+S-V,S-V: Mặc dù........mà

Tom failed the exam in spite of working very hard. 
 Even though_Tom worked very hard, Tom failed the exam

5. In spite of getting the highest result in the class, Linda still had problems with the teacher
 Even though_Linda got highest result in the class, she still had problems with the teacher 
 6. Despite/in spite of being a little overweight, he is actually quite fit.
 Even though he is a little overweight, he is actually quite fit.
 7. Although he had a good salary, he was unhappy in his job. 
 In spite of having a good salary, he was unhappy in his job. 
8. Although she earned a low salary, she gave money to her parents
=> Despite / In spite of earning a low salary, she gave money to her parents
9. Although she has a physical handicap, she has become a successful woman.
=> Despite having a physical handicap, she has become a successful woman.
10. Despite being tired, he walked to the station. 
 Although he was tired, he walked to the station.